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Germ Cell Tumors

Tumors primarily composed of germ cells are known as germ cell tumors, and they can be either malignant (cancerous) or nonmalignant (non-cancerous, benign). The cells that form in the embryo (fetus or unborn child) and eventually give rise to the cells that make up the reproductive systems of both males and females are known as germ cells. The germ cells that descend into the scrotal sac as testicular cells or into the pelvis as ovarian cells are referred to as such. Germ cells are the source of the majority of testicular and ovarian cancers. The term "gonads" refers to the ovaries and testes. Germ cell cancers are not common. It is possible for germ cell cancers to spread to other body parts.

The most typical signs and symptoms of germ cell tumors are listed below. But each person experiences symptoms differently, and they can change based on the location and size of the tumor.
  • A detectable or palpable tumor, bulge, or bulk
  • Increased alpha-fetoprotein, or AFP, levels
  • Increased beta-human chorionic gonadotropin (ß-HCG) levels
  • Stomach ache
  • Breathing difficulties or wheezing in case of spread to the lungs

Be in contact with the Best Medical Oncologist in Ahmedabad, Dr. Manasi Shah if you encounter any of the aforementioned symptoms, as they may also be indicative of other ailments.

A thorough medical history and physical examination are conducted, and diagnostic techniques for the same are as follows:
  • Biopsy: Using a microscope to examine the tissue sample taken from the tumor.
  • Tumor markers: A certain volume of blood is used to measure the size, quantity, and maturity of various blood cells.
  • Several imaging examinations, including the CT scan, Ultrasound, MRI, X-ray, and Bone scans

Once the ovarian cancer is found in a patient, the following step is to stage the disease so that a personalized, effective treatment plan may be developed.

Treatment possibilities include the following, either separately or in combination.
  • Surgery
  • Chemotherapy
  • Radiation
  • Supportive care following a bone marrow transplant (for the effects of treatment)
  • Replenishment of hormones (if necessary)
  • Ongoing follow-up care (to monitor therapy side effects, identify recurrence of disease, and assess response to treatment)
A doctor's decision about treatment will take into account the following factors:
  • Age, general health, and medical history
  • The severity of the illness